If antigens enter through the skin, where are they likely to go?

• A. Lymph vessels and nodes
• B. Spleen
• C. Bone marrow
• D. Liver

Answer: (A)

When antigens enter the body through the skin, they are typically captured by dendritic cells and other immune cells residing in the skin. These cells play a crucial role in the immune response by processing the antigens and then migrating to nearby lymphatic vessels.

The lymphatic vessels transport the processed antigens to lymph nodes, which are key sites for the activation of the adaptive immune response. Within the lymph nodes, T cells and B cells can further respond to these antigens, leading to the production of antibodies and the activation of other immune functions. This pathway highlights the critical role of the lymphatic system in monitoring and responding to potential pathogens that breach the body's first line of defense, which is the skin.

Thus, the route through lymph vessels and nodes is integral to the immune mechanism that handles antigens introduced via the skin, making it the correct answer in understanding how the body responds to skin-entrapping antigens.